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Sunday, September 7, 1980 - 1:00PM
San Francisco 49ers  26  vs
New Orleans Saints  23
at Louisiana Superdome, New Orleans, LA
CBS - Frank Glieber, Roger Staubach
Head To Head for:
San Francisco vs New Orleans
Sunday, September 14, 1980 - 4:00PM
St. Louis Cardinals  21  vs
San Francisco 49ers  24  OT
at Candlestick Park, San Francisco, CA
CBS - Curt Gowdy, Hank Stram
Head To Head for:
St. Louis vs San Francisco
Sunday, September 21, 1980 - 1:00PM
San Francisco 49ers  37  vs
New York Jets  27
at Shea Stadium, New York, NY
CBS - Lindsey Nelson, Sonny Jurgensen
Head To Head for:
San Francisco vs New York
Sunday, September 28, 1980 - 4:00PM
Atlanta Falcons  20  vs
San Francisco 49ers  17
at Candlestick Park, San Francisco, CA
CBS - Vin Scully, George Allen
Head To Head for:
Atlanta vs San Francisco
Sunday, October 5, 1980 - 4:00PM
San Francisco 49ers  26  vs
Los Angeles Rams  48
at Anaheim Stadium, Anaheim, CA
CBS - Vin Scully, George Allen
Head To Head for:
San Francisco vs Los Angeles
Sunday, October 12, 1980 - 1:00PM
San Francisco 49ers  14  vs
Dallas Cowboys  59
at Texas Stadium, Irving, TX
CBS - Frank Glieber, Roger Staubach
Head To Head for:
San Francisco vs Dallas
Sunday, October 19, 1980 - 4:00PM
Los Angeles Rams  31  vs
San Francisco 49ers  17
at Candlestick Park, San Francisco, CA
CBS - Gary Bender, John Madden
Head To Head for:
Los Angeles vs San Francisco
Sunday, October 26, 1980 - 4:00PM
Tampa Bay Buccaneers  24  vs
San Francisco 49ers  23
at Candlestick Park, San Francisco, CA
CBS - Frank Glieber, Jim Hill
Head To Head for:
Tampa Bay vs San Francisco
Sunday, November 2, 1980 - 1:00PM
San Francisco 49ers  13  vs
Detroit Lions  17
at Pontiac Silver Dome, Pontiac, MI
CBS - Tim Ryan, Johnny Morris
Head To Head for:
San Francisco vs Detroit
Sunday, November 9, 1980 - 1:00PM
San Francisco 49ers  16  vs
Green Bay Packers  23
at Milwaukee County Stadium, Milwaukee, WI
CBS - Lindsey Nelson, Sonny Jurgensen
Head To Head for:
San Francisco vs Green Bay
Sunday, November 16, 1980 - 4:00PM
San Francisco 49ers  13  vs
Miami Dolphins  17
at Miami Orange Bowl, Miami, FL
CBS - Curt Gowdy, Hank Stram
Head To Head for:
San Francisco vs Miami
Sunday, November 23, 1980 - 4:00PM
New York Giants  0  vs
San Francisco 49ers  12
at Candlestick Park, San Francisco, CA
CBS - Gary Bender, John Madden
Head To Head for:
New York vs San Francisco
Sunday, November 30, 1980 - 4:00PM
New England Patriots  17  vs
San Francisco 49ers  21
at Candlestick Park, San Francisco, CA
NBC - Sam Nover, Bob Trumpy
Head To Head for:
New England vs San Francisco
Sunday, December 7, 1980 - 4:00PM
New Orleans Saints  35  vs
San Francisco 49ers  38  OT
at Candlestick Park, San Francisco, CA
CBS - Jim Kelly, Jim Hill
NO lead 35-7 at halftime.
Head To Head for:
New Orleans vs San Francisco
Sunday, December 14, 1980 - 1:00PM
San Francisco 49ers  10  vs
Atlanta Falcons  35
at Atlanta-Fulton County Stadium, Atlanta, GA
CBS - Gary Bender, John Madden
Head To Head for:
San Francisco vs Atlanta
Sunday, December 21, 1980 - 4:00PM
Buffalo Bills  18  vs
San Francisco 49ers  13
at Candlestick Park, San Francisco, CA
NBC - Don Criqui, Mike Haffner
Head To Head for:
Buffalo vs San Francisco